Mr. Brownstone is a hard rock composition primarily written by Guns N' Roses rhythm guitarist Izzy Stradlin with musical collaboration from lead guitarist Slash, first recorded for the band's 1987 debut album Appetite for Destruction. The song holds a notable place in the band's history as the first composition they wrote after signing with Geffen Records. It originated during the album's recording sessions when Stradlin and Slash were improvising together at Stradlin's apartment, with the initial lyrics and music scrawled on the back of a grocery bag. The composition is built on a distinctive blues-based rhythmic foundation that draws directly from the Bo Diddley beat, a syncopated pattern rooted in 1950s rock and roll. Drummer Steven Adler's driving interpretation of this rhythm provides what has been described as the track's racing heartbeat, propelling the song forward through angular, blues-soaked riffs rather than harmonic complexity. The title is slang for heroin, and the lyrics use narrative storytelling to depict the escalating grip of addiction. The song took on additional weight within the band's trajectory when Axl Rose began using live performances of it as a vehicle for confronting bandmates about their substance abuse, notably during their October 1989 opening shows for the Rolling Stones. Released as the band's first international single as a double A-side with It's So Easy, it helped establish their early commercial presence.