"Lou's Blues" is a burning blues original by alto saxophonist Lou Donaldson from A Night at Birdland Vol. 2, recorded live by the Art Blakey Quintet in 1954. Set as a 12-bar blues in B-flat at a ferocious tempo exceeding 315 bpm, the tune is one of the fastest performances in the entire Birdland series. Donaldson leads with five choruses of alto saxophone, his tone bright and cutting as he navigates the blues changes at breakneck speed. Clifford Brown follows with nine astonishing trumpet choruses, constructing a solo of remarkable coherence and invention despite the extreme tempo. Horace Silver closes the solo section with seven choruses of rhythmically propulsive piano. The sheer velocity of the performance is thrilling, yet none of the soloists resort to mere technical display; each maintains a strong sense of melody and blues feeling throughout. As a Donaldson original, the tune reflects his deep roots in the blues tradition and his ability to channel that tradition into the most demanding bebop contexts. This track serves as a fitting closer to the Birdland Vol. 2 album, leaving listeners breathless with the quintet's seemingly limitless energy.